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A fluid intake sufficient to yield a daily urinary output of at least 2 liters and the maintenance of a neutral orpreferablyslightly alkaline urine are desirable to1avoid the theoretical possibility of formation of xanthine calculi under the influence of therapy with Zyloprim and2help prevent renal precipitation of urates in patients receiving concomitant uricosuric agents.

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Due to the occasional occurrence of drowsinesspatients should be alerted to the need for due precaution when engaging in activities where alertness is mandatory.

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