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A small amount of radioactivity has been found in the milk of lactating rats after administration of radiolabeled acarboseIt is not known whether this drug is excreted in human milkBecause many drugs are excreted in human milkPrecose should not be administered to a nursing woman.
There have been rare postmarketing reports of pneumatosis cystoides intestinalis associated with the use of alpha-glucosidase inhibitorsincluding PrecosePneumatosis cystoides intestinalis may present with symptoms of diarrheamucus dischargerectal bleedingand constipationComplications may include pneumoperitoneumvolvulusintestinal obstructionintussusceptionintestinal hemorrhageand intestinal perforationIf pneumatosis cystoides intestinalis is suspecteddiscontinue Precose and perform the appropriate diagnostic imaging.
Results from these six fixed-dosemonotherapy studies were also combined to derive a weighted average of the difference from placebo in mean change from baseline for one-hour postprandial plasma glucose levels as shown in the following figure:
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