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Clinical trials did not reveal any tendency for withdrawal syndrome when you stop taking zoloft or drug-seeking behavior that is typical of drugthat produce a high.

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Patients in Study PMDD-1 met DSM-III-R criteria for Late Luteal Phase Dysphoric DisorderLLPDDthe clinical entity referred to as PMDD in DSM-IVPatients in Study PMDD-2 met DSM-IV criteria for PMDDStudy PMDD-1 utilized continuous daily dosing throughout the studywhile Study PMDD-2 utilized luteal phase dosingintermittent dosingfor the 2 weeks prior to the onset of mensesThe mean duration of PMDD symptoms was approximately 10.5 years in both studiesPatients taking oral contraceptives were excluded from these trialsthereforethe efficacy of ZOLOFT in combination with oral contraceptives for the treatment of PMDD is unknown.

Take the dose of Zoloft when you rememberbut skip the missed dose if it is almost time for your next doseYou should never take extra doses of the medication to make up for missed doses.

Do not take sertraline if you have used an MAO inhibitor such as furazolidoneFuroxoneisocarboxazidMarplanphenelzineNardilrasagilineAzilectselegilineEldeprylEmsamZelaparor tranylcypromineParnatein the last 14 daysA dangerous drug interaction could occurleading to serious side effects.

In a published pooled analysis of 53 mother-infant pairsexclusively human milk-fed infants had an average of 2range 0to 15of the sertraline serum levels measured in their mothersNo adverse reactions were observed in these infants.

Inform patients not to take disulfiram when taking ZOLOFT oral solutionConcomitant use is contraindicated due the alcohol content of the oral solutionsee CONTRAINDICATIONS

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