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If hypersensitivity reactions occur, discontinue use of zofran; treat promptly per standard of care and monitor until signs and symptoms resolve see contraindications .

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Although ZofranZuplenz and the generic ondansetron are FDA-approved only for use in treating nausea and vomiting after chemotherapy or radiotherapy or after surgerymany doctors prescribe them for off-label usesincluding treatment of morning sickness in expectant mothers.

It is not known whether ondansetron passes into breast milk or if it could harm a nursing babyDo not use this medication without telling your doctor if you are breast-feeding a baby.

Liver diseaseheart diseasecongestive heart failurea heart rhythm disorderan electrolyte imbalancesuch as low levels of potassium or magnesium in your bloodor a personal or family history of Long QT syndrome.

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