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Zyban medicine may impair your thinking processes; therefore, avoid the tasks that need proper concentration such as driving or operating heavy machinery alcoholic preparation and grapefruit juices should be kept aside along the time being treated with zyban as these may reduce the beneficial effect of zyban medicine.

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When beginningthe medicationusers will first take the Champix Starter PackThis contains two different strengths of tablet and covers the first two weeks of the course.

Zyban tablets are indicated as an aid to smoking cessation in combination with motivational support in nicotine-dependent patients.

Get emergency medical help if you have any of these signs of an allergic reaction to Zybanhivesdifficult breathingswelling of your facelipstongueor throat.

Some epidemiological studies of pregnancy outcomes following maternal exposure to bupropion in the first trimester have reported an association with increased risk of certain congenital cardiovascular malformations specifically ventricular septal defects and left outflow tract heart defectsThese findings are not consistent across studiesAnimal studies do not indicate direct or indirect harmful effects with respect to reproductive toxicitysee section 5.3Zyban should not be used in pregnancyPregnant women should be encouraged to quit smoking without the use of pharmacotherapy.

Limited clinical trial data suggest that higher smoking cessation rates may be achieved by the combination use of Zyban together with Nicotine Transdermal SystemNTSHowevera higher rate of treatment-emergent hypertension was noted in the combination therapy groupIf combination therapy with a NTS is usedcaution must be exercised and weekly monitoring of blood pressure is recommendedPrior to initiation of combination therapy prescribers should consult the prescribing information of the relevant NTS.

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